The impact of chronic kidney disease Stages 3-5 on pregnancy outcomes.

ABSTRACT:

Background

Contemporaneous data are required for women with chronic kidney disease (CKD) Stages 3-5 to inform pre-pregnancy counselling and institute appropriate antenatal surveillance.

Methods

A retrospective cohort study in women with CKD Stages 3-5 after 20 weeks' gestation was undertaken in six UK tertiary renal centres in the UK between 2003 and 2017. Factors predicting adverse outcomes and the impact of pregnancy in accelerating the need for renal replacement therapy (RRT) were assessed.

Results

There were 178 pregnancies in 159 women, including 43 women with renal transplants. The live birth rate was 98%, but 56% of babies were born preterm (before 37 weeks' gestation). Chronic hypertension was the strongest predictor of delivery before 34 weeks' gestation. Of

SUBMITTER: Wiles K 

PROVIDER: S-EPMC8577624 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature