Ancestral Background Is Underreported in Regenerative Engineering.

ABSTRACT:

Purpose

The ancestral background of human cells may play a role in cells' behavior and response to therapeutic interventions in vitro. We investigate the prevalence of ancestry reporting in current biological research and suggest that increased reporting would be beneficial to the field.

Methods

Articles published over a six-month period in ten different journals were reviewed for their use of human primary cells and immortalized cell lines, and were analyzed based on whether or not the ancestral or ethnic information of cell donors was ascertainable.

Results

The vast majority of literature published in the journals and timeframe we investigated did not report on the ancestral or ethnic origins of the human cells used.

Conclusion

There is currently a substantia

SUBMITTER: Ryan H 

PROVIDER: S-EPMC8577639 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature