Proteomics Analysis of Serum Proteins in Gestational Diabetes.

ABSTRACT:

Objective

The purpose of this study was to screen serum proteins for biomarkers of gestational diabetes mellitus (GDM) and to investigate its pathogenesis by analyzing the differences in serum proteomics between pregnant women with GDM and healthy pregnant women.

Methods

Patients who were admitted to the First Affiliated Hospital of Fujian Medical University from June 2019 to January 2020 were included. According to the medical history and the results of the 75 g oral glucose tolerance test (OGTT), they were divided into the normal pregnant women group and GDM pregnant women group. The serum of two groups of patients was collected. High performance liquid chromatography-mass spectrometry was used to identify differentially expressed serum proteins between pregnant women with

SUBMITTER: Li J 

PROVIDER: S-EPMC8577917 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature