Defining mechanisms of recurrence following apical prolapse repair based on imaging criteria.

ABSTRACT:

Background

Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate of anatomic recurrence and to develop novel therapies to overcome defined deficiencies.

Objective

This study aimed to identify mechanisms and contributors of anatomic recurrence after vaginal hysterectomy with uterosacral ligament suspension (native tissue repair) vs transvaginal mesh (VM) hysteropexy surgery for uterovaginal prolapse.

Study design

This multicenter study was conducted in a subset of participants in a randomized clinical trial by the Eunice Kennedy Shriver National Institute of Child Health and Human Development Pelvic Floor Disorders Netw

SUBMITTER: Bowen ST 

PROVIDER: S-EPMC8578187 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature