Decreased biofilm formation in Proteus mirabilis after short-term exposure to a simulated microgravity environment.

ABSTRACT:

Background

Microbes threaten human health in space exploration. Studies have shown that Proteus mirabilis has been found in human space habitats. In addition, the biological characteristics of P. mirabilis in space have been studied unconditionally. The simulated microgravity environment provides a platform for understanding the changes in the biological characteristics of P. mirabilis.

Objective

This study intends to explore the effect of simulated microgravity on P. mirabilis, the formation of P. mirabilis biofilm, and its related mechanism.

Methods

The strange deformable rods were cultured continuously for 14 days under microgravity simulated in high-aspect rotating vessels (HARVs). The morphology, growth rate, metabolism, and biofilm formation of the strain were m

SUBMITTER: Wang D 

PROVIDER: S-EPMC8578233 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature