Selective isolation of foot-and-mouth disease virus from coinfected samples containing more than one serotype.

ABSTRACT: The foot-and-mouth disease virus (FMDV) causes a highly infectious disease of all cloven-footed animals. The RNA genome of the virus continuously evolves, leading to the generation of new strains; this necessitates the selection of new vaccine strains to ensure complete protection. Infection with one FMDV serotype does not provide cross-protection against the other FMDV serotypes. Many of the recovered animals may become carriers of the FMDV, but they still remain susceptible to the other serotypes. Coinfection with multiple FMDV serotypes has been reported and studied to understand the virus evolution. Isolation and characterization of all the involved serotypes in the mixed infection case is essential to understand the molecular evolution of the virus. In this study, two cases of coinfec

SUBMITTER: Mahajan S 

PROVIDER: S-EPMC8578238 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature