Acute ambient air pollution exposure and placental Doppler results in the NICHD fetal growth studies - Singleton cohort.

ABSTRACT:

Background

Increased placental vascular resistance is a proposed mechanism by which air pollution exposure during pregnancy lowers birth weight and increases pregnancy-induced hypertensive disorders.

Objective

To examine the impact of acute air pollution exposure during pregnancy on uterine and umbilical artery Doppler indicators of placental vascular resistance.

Methods

After a first ultrasound to confirm gestational age, 2562 pregnant women recruited in 12 clinics throughout the United States underwent up to five standardized ultrasounds with Doppler measurements. Exposures to 11 air pollutants were estimated for the hour of ultrasound and each of the 2 h prior to ultrasound at the clinics using the National Air Quality Forecast Capability reanalysis products. We us

SUBMITTER: Ouidir M 

PROVIDER: S-EPMC8578287 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature