A histopathological and immunohistochemical study of experimental infected turkeys with a virulent Newcastle disease virus.

ABSTRACT: Newcastle disease (ND) is a highly contagious infection of many avian species, mainly chickens and turkeys, with a devastating impact on worldwide poultry production. This study was designed to examine the effect of virulent ND infection in turkey's tissues and the tissue tropism of the virus. During the previous study period, poults were inoculated at 32 days of age with 10⁵ EID50 virulent Newcastle disease virus. Three poults on days 0, 1, 2, 3, 4, 6, 7, and 14 postinoculations (PI) were selected from each group. They were euthanized by intravenous sodium pentobarbital injection. After macroscopic observation, to histopathological and immunohistochemical studies, the spleen, bursa, cecal tonsils, intestine, proventriculus, lung, kidney, and brain were sampled. Clinically, the

SUBMITTER: Saravi AN 

PROVIDER: S-EPMC8578479 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature