An Overview of Registered Clinical Trials on Glucosinolates and Human Health: The Current Situation.

ABSTRACT: Epidemiological studies suggest a potential role of glucosinolates (GSLs) and isothiocyanates on human health. However, evidence from intervention studies, due to heterogeneity in features of study design, duration, participants, food or food components administered, and outcomes analyzed, is still insufficient. The current review aims to provide an overview of the trials on GSLs and GSL-rich foods registered over the last 20 years with the intention to summarize the main topics and results, but also the existing gaps that still need to be covered. Studies were collected by using ClinicalTrials.gov and the International Standard Randomized Controlled Trial Number (ISRCTN) registry. A total of 87 registered trials were identified with which most of them were performed by using extracts or p

SUBMITTER: Marino M 

PROVIDER: S-EPMC8578719 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature