Identification of the clinical and neuroimaging characteristics in children with neuromyelitis optica spectrum disorders: a case series.

ABSTRACT:

Background

Childhood neuromyelitis optica spectrum disorders (NMOSDs) may cause visual impairment and brain or spinal cord damage, and the effects may be permanent if left untreated. Since the incidence of NMOSD cases in children is relatively low, the understanding of NMOSD among children is inadequate.

Methods

This investigation examined the clinical and neuroimaging characteristics of childhood NMOSD. We retrospectively analyzed the clinical information of 11 NMOSD patients admitted to our centre from 2012 to 2021. The disease status was assessed by the Expanded Disability Status Scale (EDSS) score.

Results

The two major symptoms observed in the study cohort were optic neuritis (ON) (9/11) and encephalopathy (7/11). Antibody tests were performed on 8 children, 2 of

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC8578765 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature