Challenges and Solutions in translating sepsis guidelines into practice in resource-limited settings.

ABSTRACT: Sepsis and septic shock are major contributors to the global burden of disease, with a large proportion of patients and deaths with sepsis estimated to occur in low- and middle-income countries (LMICs). There are numerous barriers to reducing the large global burden of sepsis including challenges in quantifying attributable morbidity and mortality, poverty, inadequate awareness, health inequity, under-resourced public health, and low-resilient acute health care delivery systems. Context-specific approaches to this significant problem are necessary on account of important differences in populations at-risk, the nature of infecting pathogens, and the healthcare capacity to manage sepsis in LMIC. We review these challenges and propose an outline of some solutions to tackle them which include

SUBMITTER: Ranjit S 

PROVIDER: S-EPMC8578780 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature