Effect of voluntary exercise upon the metabolic syndrome and gut microbiome composition in mice.

ABSTRACT: The metabolic syndrome is a cluster of conditions that increase an individual's risk of developing diseases. Being physically active throughout life is known to reduce the prevalence and onset of some aspects of the metabolic syndrome. Furthermore, previous studies have demonstrated that an individual's gut microbiome composition has a large influence on several aspects of the metabolic syndrome. However, the mechanism(s) by which physical activity may improve metabolic health are not well understood. We sought to determine if endurance exercise is sufficient to prevent or ameliorate the development of the metabolic syndrome and its associated diseases. We also analyzed the impact of physical activity under metabolic syndrome progression upon the gut microbiome composition. Utilizing whole

SUBMITTER: Moore TM 

PROVIDER: S-EPMC8578881 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature