Ontology highlight
ABSTRACT:
SUBMITTER: Lin L
PROVIDER: S-EPMC8578896 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Lin Li L Huang Kai K Tu Zewei Z Zhu Xingen X Li Jingying J Lei Kunjian K Luo Min M Wang Peng P Gong Chuandong C Long Xiaoyan X Wu Lei L
Frontiers in oncology 20211027
Diffuse gliomas are the most common malignant brain tumors with the highest mortality and recurrence rate in adults. Integrin alpha-2 (ITGA2) is involved in a series of biological processes, including cell adhesion, stemness regulation, angiogenesis, and immune/blood cell functions. The role of ITGA2 in lower-grade gliomas (LGGs) is not well defined. Firstly, we downloaded RNA sequencing and relevant clinical information from The Cancer Genome Atlas cohort, the Chinese Glioma Genome Atlas cohort ...[more]