Epinephrine before defibrillation in patients with shockable in-hospital cardiac arrest: propensity matched analysis.

ABSTRACT:

Objective

To determine the use of epinephrine (adrenaline) before defibrillation for treatment of in-hospital cardiac arrest due to a ventricular arrhythmia and examine its association with patient survival.

Design

Propensity matched analysis.

Setting

2000-18 data from 497 hospitals participating in the American Heart Association’s Get With The Guidelines-Resuscitation registry.

Participants

Adults aged 18 and older with an index in-hospital cardiac arrest due to an initial shockable rhythm treated with defibrillation.

Interventions

Administration of epinephrine before first defibrillation.

Main outcome measures

Survival to discharge; favorable neurological survival, defined as survival to discharge with none, mild, or moderate neurological disabi

SUBMITTER: Evans E 

PROVIDER: S-EPMC8579224 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature