Impact of Right Ventricular Dysfunction on Short-term and Long-term Mortality in Sepsis: A Meta-analysis of 1,373 Patients.

ABSTRACT:

Background

Right ventricular (RV) dysfunction in sepsis and septic shock has been infrequently studied and has uncertain prognostic significance.

Research question

Does RV function impact mortality in sepsis and septic shock?

Study design and methods

We reviewed the published literature from January 1999 to April 2020 for studies evaluating adult patients with sepsis and septic shock. Study definition of RV dysfunction was used to classify patients. The primary outcome was all-cause mortality divided into short-term mortality (ICU stay, hospital stay, or mortality ≤30 days) and long-term mortality (>30 days). Effect estimates from the individual studies were extracted and combined, using the random-effects, generic inverse variance method of DerSimonian and Laird.

SUBMITTER: Vallabhajosyula S 

PROVIDER: S-EPMC8579312 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature