The ensemble learning model is not better than the Asian modified CKD-EPI equation for glomerular filtration rate estimation in Chinese CKD patients in the external validation study.

ABSTRACT:

Objective

To assess the clinical practicability of the ensemble learning model established by Liu et al. in estimating glomerular filtration rate (GFR) and validate whether it is a better model than the Asian modified Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation in a cohort of Chinese chronic kidney disease (CKD) patients in an external validation study.

Methods

According to the ensemble learning model and the Asian modified CKD-EPI equation, we calculated estimated GFR_ensemble and GFR_CKD-EPI, separately. Diagnostic performance of the two models was assessed and compared by correlation coefficient, regression equation, Bland-Altman analysis, bias, precision and P₃₀ under the premise of ^99mTc-diethylenetriami

SUBMITTER: Zhao L 

PROVIDER: S-EPMC8579608 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature