Ontology highlight
ABSTRACT:
SUBMITTER: Tebani A
PROVIDER: S-EPMC8579660 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Tebani Abdellah A Jotanovic Jelena J Hekmati Neda N Sivertsson Åsa Å Gudjonsson Olafur O Edén Engström Britt B Wikström Johan J Uhlèn Mathias M Casar-Borota Olivera O Pontén Fredrik F
Acta neuropathologica communications 20211110 1
Pituitary neuroendocrine tumors (PitNETs) are common, generally benign tumors with complex clinical characteristics related to hormone hypersecretion and/or growing sellar tumor mass. PitNETs can be classified based on the expression pattern of anterior pituitary hormones and three main transcriptions factors (TF), SF1, PIT1 and TPIT that regulate differentiation of adenohypophysial cells. Here, we have extended this classification based on the global transcriptomics landscape using tumor tissue ...[more]