Perspectives on extended-release naltrexone induction among patients living with HIV and opioid use disorder: a qualitative analysis.

ABSTRACT:

Background

The CHOICES study randomized participants with HIV and opioid use disorder (OUD) to HIV clinic-based extended-release naltrexone (XR-NTX), which requires complete cessation of opioid use, versus treatment-as-usual (i.e., buprenorphine, methadone). Study participants randomized to XR-NTX were interviewed to assess their experiences with successful and unsuccessful XR-NTX induction.

Methods

Semi-structured qualitative interviews were completed with a convenience sample of study participants with HIV and OUD (n = 37) randomized to XR-NTX in five HIV clinics between 2018 and 2019. All participants approached agreed to be interviewed. Interviews were digitally recorded, professionally transcribed, and analyzed using thematic analysis.

Results

Participants includ

SUBMITTER: Hoffman KA 

PROVIDER: S-EPMC8579672 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature