The Impact of Embryo Storage Time on Pregnancy and Perinatal Outcomes and the Time Limit of Vitrification: A Retrospective Cohort Study.

ABSTRACT:

Background

The technique of embryo cryopreservation has been increasingly applied in clinical settings. However, there has been a concern about the safety and efficacy of long-term freezing of embryos. Therefore, the aim of this study was to evaluate whether storage time of vitrification had any effects on pregnancy as well as perinatal outcomes, further, to explore the appropriate time limit of vitrification.

Methods

The study included women who underwent at least one frozen-thawed cycle with single embryo transfer between January 1^st, 2016 and September 30^th, 2019. Patients were assigned into 3 groups according to the storage time (<3 months, 3-12 months and >12 months) to evaluate the impact of embryo storage time on pregnancy and perinatal outcomes.

SUBMITTER: Cui M 

PROVIDER: S-EPMC8579853 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature