Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations.

ABSTRACT: Evolutionary adaptation to a constant environment is driven by the accumulation of mutations which can have a range of unrealized pleiotropic effects in other environments. These pleiotropic consequences of adaptation can influence the emergence of specialists or generalists, and are critical for evolution in temporally or spatially fluctuating environments. While many experiments have examined the pleiotropic effects of adaptation at a snapshot in time, very few have observed the dynamics by which these effects emerge and evolve. Here, we propagated hundreds of diploid and haploid laboratory budding yeast populations in each of three environments, and then assayed their fitness in multiple environments over 1000 generations of evolution. We find that replicate populations evolved in the s

SUBMITTER: Bakerlee CW 

PROVIDER: S-EPMC8579951 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature