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Visible light-induced oxidative N-dealkylation of alkylamines by a luminescent osmium(vi) nitrido complex.

ABSTRACT: N-Dealkylation of amines by metal oxo intermediates (M[double bond, length as m-dash]O) is related to drug detoxification and DNA repair in biological systems. In this study, we report the first example of N-dealkylation of various alkylamines by a luminescent osmium(vi) nitrido complex induced by visible light.

SUBMITTER: Xiang J

PROVIDER: S-EPMC8580045 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Visible light-induced oxidative N-dealkylation of alkylamines by a luminescent osmium(vi) nitrido complex.

Xiang Jing J Peng Min M Pan Yi Y Luo Li-Juan LJ Cheng Shun-Cheung SC Jin Xin-Xin XX Yiu Shek-Man SM Man Wai-Lun WL Ko Chi-Chiu CC Lau Kai-Chung KC Lau Tai-Chu TC

Chemical science 20211009 43

N-Dealkylation of amines by metal oxo intermediates (M[double bond, length as m-dash]O) is related to drug detoxification and DNA repair in biological systems. In this study, we report the first example of N-dealkylation of various alkylamines by a luminescent osmium(vi) nitrido complex induced by visible light. ...[more]

PMID: 34881000

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