A network pharmacology approach to explore the potential role of Panax ginseng on exercise performance.

ABSTRACT:

Purpose

As Panax ginseng C. A. Meyer (ginseng) exhibits various physiological activities and is associated with exercise, we investigated the potential active components of ginseng and related target genes through network pharmacological analysis. Additionally, we analyzed the association between ginseng-related genes, such as the G-protein-coupled receptors (GPCRs), and improved exercise capacity.

Methods

Active compounds in ginseng and the related target genes were searched in the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). Gene ontology functional analysis was performed to identify biological processes related to the collected genes, and a compound-target network was visualized using Cytoscape 3.7.2.

Results

A total of 21 ginseng active com

SUBMITTER: Kim J 

PROVIDER: S-EPMC8580580 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature