¹⁸F-PSMA-1007 PET/CT Performance on Risk Stratification Discrimination and Distant Metastases Prediction in Newly Diagnosed Prostate Cancer.

ABSTRACT:

Objective

To evaluate the prediction performance of ¹⁸F-PSMA-1007 PET/CT and clinicopathologic characteristics on prostate cancer (PCa) risk stratification and distant metastatic prediction.

Materials and methods

A retrospective analysis was performed on 101 consecutively patients with biopsy or radical prostatectomy proved PCa who underwent ¹⁸F-PSMA-1007 PET/CT. The semi-quantitative analysis provided minimum, maximum and mean standardized uptake (SUVmin, SUVmax and SUVmean) of PCa. Association between clinicopathologic characteristics (total prostate-specific antigen, tPSA and Gleason Score, GS) and PET/CT indexes were analyzed. The diagnostic performance of distant metastatic on PET/CT parameters, tPSA and GS was evaluated using logistic regression a

SUBMITTER: Wang Z 

PROVIDER: S-EPMC8581554 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature