Measuring neuropsychiatric symptoms in patients with early cognitive decline using speech analysis.

ABSTRACT:

Background

Certain neuropsychiatric symptoms (NPS), namely apathy, depression, and anxiety demonstrated great value in predicting dementia progression, representing eventually an opportunity window for timely diagnosis and treatment. However, sensitive and objective markers of these symptoms are still missing. Therefore, the present study aims to investigate the association between automatically extracted speech features and NPS in patients with mild neurocognitive disorders.

Methods

Speech of 141 patients aged 65 or older with neurocognitive disorder was recorded while performing two short narrative speech tasks. NPS were assessed by the neuropsychiatric inventory. Paralinguistic markers relating to prosodic, formant, source, and temporal qualities of speech were automatica

SUBMITTER: Konig A 

PROVIDER: S-EPMC8581700 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature