The effect of dobutamine in sepsis: a propensity score matched analysis.

ABSTRACT:

Background

The use of dobutamine in patients with sepsis is questionable currently. As the benefit of dobutamine in septic patients is unclear, we aimed to evaluate whether the use of dobutamine was associated with decreased hospital mortality in sepsis patients.

Methods

Based on the analysis of MIMIC III public database, we performed a big-data, real world study. According to the use of dobutamine or not, patients were categorized as the dobutamine group or non dobutamine group.We used propensity score matched (PSM) analysis to adjust for confoundings. The primary outcome was hospital mortality.

Results

In the present study, after screening 38,605 patients, 2826 patients with sepsis were included. 121 patients were in dobutamine group and 2165 patients were in non do

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC8582172 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature