The composition of lung microbiome in lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Although recent studies have indicated that imbalance in the respiratory microbiome composition is linked to several chronic respiratory diseases, the association between the lung microbiome and lung cancer has not been extensively studied. Conflicting reports of individual studies on respiratory microbiome alterations in lung cancer complicate the matter for specifying how the lung microbiome is linked to lung cancer. Consequently, as the first meta-analysis on this topic, we integrate publicly available 16S rRNA gene sequence data on lung tissue samples of lung cancer patients to identify bacterial taxa which differ consistently between case and control groups.

Results

The findings of the current study suggest that the relative abundance of several bacterial tax

SUBMITTER: Najafi S 

PROVIDER: S-EPMC8582175 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature