Radiological Patterns of Uveal Melanoma Liver Metastases in Correlation to Genetic Status.

ABSTRACT: This study reports the role played by the mutation status of Uveal Melanoma (UM) in relation to hepatic metastatic patterns as seen on imaging modalities. Radiological images were obtained from 123 patients treated at the Erasmus Medical Center Rotterdam or the Rotterdam Eye Hospital. Radiological images were derived from either computed tomography or magnetic resonance imaging. Hepatic metastatic patterns were classified by counting the number of metastases found in the liver. Miliary metastatic pattern (innumerable small metastases in the entire liver) was analyzed separately. Mutation status was determined in 85 patients. Median disease-free survival (DFS) and survival with metastases differed significantly between each of the metastatic patterns (respectively, p = 0.009, p < 0.001), bo

SUBMITTER: Yavuzyigitoglu S 

PROVIDER: S-EPMC8582397 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature