Characteristics and growth of the genetic HIV transmission network of Mexico City during 2020.

ABSTRACT:

Introduction

Molecular surveillance systems could provide public health benefits to focus strategies to improve the HIV care continuum. Here, we infer the HIV genetic network of Mexico City in 2020, and identify actively growing clusters that could represent relevant targets for intervention.

Methods

All new diagnoses, referrals from other institutions, as well as persons returning to care, enrolling at the largest HIV clinic in Mexico City were invited to participate in the study. The network was inferred from HIV pol sequences, using pairwise genetic distance methods, with a locally hosted, secure version of the HIV-TRACE tool: Seguro HIV-TRACE. Socio-demographic, clinical and behavioural metadata were overlaid across the network to design focused prevention interventions.

SUBMITTER: Davila-Conn V 

PROVIDER: S-EPMC8583431 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature