Interstitial Lung Disease in Connective Tissue Diseases: Survival Patterns in a Population-Based Cohort.

ABSTRACT: Interstitial lung disease (ILD) is associated with impaired survival among patients with connective tissue diseases (CTDs), but population-based data on the frequency of ILD and pulmonary hypertension (PH) in different CTD subtypes and the impact on survival are sparse. We included patients with a first-time ICD-10 diagnosis of systemic sclerosis (SSc), mixed connective tissue disease (MCTD), myositis, systemic lupus erythematosus (SLE), or Sjögren's disease registered in the Danish National Patient Registry between 2000 and 2015. Among these, we identified patients with ILD and PH. Using Kaplan-Meier analysis, we assessed survival for the five subtypes of CTD ± ILD and compared survival among CTD patients overall ± ILD with survival in the general population ± ILD. We identified 11,731 pa

SUBMITTER: Hyldgaard C 

PROVIDER: S-EPMC8584507 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature