Education Attainment, Intelligence and COVID-19: A Mendelian Randomization Study.

ABSTRACT: Evidence of socioeconomic inequality in COVID-19-related outcomes is emerging, with a higher risk of infection and mortality observed among individuals with lower education attainment. We aimed to evaluate the potential interventions against COVID-19 from the socioeconomic perspective, including improvement in education and intelligence. With a two-sample Mendelian randomization approach using summary statistics from the largest genome-wide association meta-analysis, univariable analysis was adopted to evaluate the total causal effects of genetically determined education attainment and intelligence on COVID-19 outcomes. Multivariable analysis was performed to dissect the potential mechanisms. Genetic predisposition to higher education attainment by 1 SD (4.2 years) was independently associ

SUBMITTER: Li GH 

PROVIDER: S-EPMC8584527 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature