Genome-wide survey and characterization of transcription factors in the silk gland of the silkworm, Bombyx mori.

ABSTRACT: Transcription factors (TFs) are key proteins that modulate gene transcription and thereby lead to changes in the gene expression profile and the subsequent alteration of cellular functions. In the silk gland (SG) of silkworm Bombyx mori, an important silk-producing insect, TFs are of vital importance in the regulation of silk protein synthesis in this organ. However, which TFs exist and express in the SG remains largely unknown. Here, we report the large-scale identification of TFs in the SG based on available full-length transcript sequences and the most recent version of silkworm genome data. In total, 348 candidate TFs were identified by strict filtration and were classified into 56 TF families. Chromosomal distribution, motif composition, and phylogenetic relationship analyses revealed

SUBMITTER: Ma Y 

PROVIDER: S-EPMC8584736 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature