A novel high performing multiplex immunoassay Multi-HTLV for serological confirmation and typing of HTLV infections.

ABSTRACT:

Background

Human T-Cell Lymphotropic Viruses (HTLV) type 1 and type 2 account for an estimated 5 to 10 million infections worldwide and are transmitted through breast feeding, sexual contacts and contaminated cellular blood components. HTLV-associated syndromes are considered as neglected diseases for which there are no vaccines or therapies available, making it particularly important to ensure the best possible diagnosis to enable proper counselling of infected persons and avoid secondary transmission. Although high quality antibody screening assays are available, currently available confirmatory tests are costly and have variable performance, with high rates of indeterminate and non-typable results reported in many regions of the world. The objective of this project was to develo

SUBMITTER: Marque L 

PROVIDER: S-EPMC8584783 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature