Evaluating the virucidal activity of four disinfectants against SARS-CoV-2.

ABSTRACT:

Background

The recent COVID-19 pandemic highlights the need for efficacious virucidal products to limit the spread of SARS-CoV-2. Several studies have suggested that alcohol-based sanitizers and some disinfectants are effective. While virucidal activity data of low-level disinfectants are lacking and some conclusions are not clear yet.

Methods

We evaluated the virucidal activity of 2 quaternary ammonium compounds (QAC) disinfectants (MICRO-CHEM PLUS and FWD), W30 (an amphoteric surfactant), and Medical EtOH against SARS-CoV-2. Suspension tests covering different concentration and contact time were performed using the integrated cell culture-qPCR method.

Results

Each of disinfectants was effective at inactivating SARS-CoV-2. MCP and FWD are highly effective within 15 s

SUBMITTER: Huang Y 

PROVIDER: S-EPMC8585555 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature