Enhanced Sp1/YY1 Expression Directs CBS Transcription to Mediate VEGF-Stimulated Pregnancy-Dependent H2S Production in Human Uterine Artery Endothelial Cells.
Enhanced Sp1/YY1 Expression Directs <i>CBS</i> Transcription to Mediate VEGF-Stimulated Pregnancy-Dependent H<sub>2</sub>S Production in Human Uterine Artery Endothelial Cells.
Project description:IL-6 family cytokines as OSM and CNTF modify angiogenesis to different degree. This study investigates to which extend treatment of endothelial cells with those cytokines can modify VEGF induced angiogenic reactions. Human umbilical vein endothelial cells (HUVECs) were stimulated for 24h by cytokines followed by RNA harvesting and processed for RNA sequencing.