Assessing the efficacy of interventions to control indoor SARS-Cov-2 transmission: An agent-based modeling approach.

ABSTRACT: Nonpharmaceutical interventions for minimizing indoor SARS-CoV-2 transmission continue to be critical tools for protecting susceptible individuals from infection, even as effective vaccines are produced and distributed globally. We developed a spatially-explicit agent-based model for simulating indoor respiratory pathogen transmission during discrete events taking place in a single room within a sub-day time frame, and used it to compare effects of four interventions on reducing secondary SARS-CoV-2 attack rates during a superspreading event by simulating a well-known case study. We found that preventing people from moving within the simulated room and efficacious mask usage appear to have the greatest effects on reducing infection risk, but multiple concurrent interventions are required t

SUBMITTER: Farthing TS 

PROVIDER: S-EPMC8588587 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature