BDNF, GDNF, NGF and Klotho levels and neurocognitive functions in acute term of schizophrenia.

ABSTRACT:

Background

Klotho and its relationship with neurotrophic factors and cognition in schizophrenia has not yet been investigated. In this study, the hypothesis that the blood serum levels of BDNF, GDNF, NGF and Klotho in schizophrenia patients and healthy controls would be related to cognitive functions was investigated.

Methods

In this study, two groups were assessed: schizophrenia patients (case group) who were hospitalised in the Psychiatry Clinic of Sakarya University Training and Research Hospital and healthy volunteers (control group). The patients were evaluated on the 1st and 20th days of their hospitalisation with the Positive and Negative Syndrome Scale (PANSS), the Brief Psychiatric Rating Scale (BPRS), the General Assessment of Functioning Scale (GAF) and the Clinic

SUBMITTER: Turkmen BA 

PROVIDER: S-EPMC8588660 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature