D-Chiro-Inositol improves testosterone levels in older hypogonadal men with low-normal testosterone: a pilot study.

ABSTRACT:

Background

Several recent journal articles report that D-chiro-inositol (DCI), primarily known as insulin second messenger, influences steroidogenesis. In particular, new evidence is arising on DCI ability to regulate aromatase expression and testosterone biosynthesis. In this regard, DCI administration could represent a good therapeutic opportunity in case of reduced levels of testosterone. Older men generally have lower testosterone concentrations than younger men, and recent randomized controlled trials have examined whether testosterone treatment might improve health outcomes in this age group. There is limited information about the safety of testosterone replacement therapy in these men, hence DCI could represent an interesting alternative for future trials. Therefore, this st

SUBMITTER: Nordio M 

PROVIDER: S-EPMC8588714 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature