Early-stage macular telangiectasia type 2 vascular abnormalities are associated with interdigitation zone disruption.

ABSTRACT:

Purpose

To investigate the relationship between disruption in different photoreceptor layers and deep capillary plexus (DCP) telangiectasias in eyes with macular telangiectasia type 2 (MacTel).

Methods

35 eyes (21 patients) with MacTel imaged with optical coherence tomography angiography (OCTA) were included. Circumscribed areas of DCP telangiectasia were traced from OCTA slabs and the corresponding spectral-domain OCT (SD-OCT) slabs were used to visualize the photoreceptor layer interdigitation zone (IZ) and ellipsoid zone (EZ). IZ attenuation, IZ loss, and EZ loss were graded by reviewing en face SD-OCT slabs for hypo-reflective areas and confirming their status on cross-sectional views. Total area of photoreceptor disruption and overlap with DCP telangiectasia were evalua

SUBMITTER: Ong JX 

PROVIDER: S-EPMC8589180 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature