Ontology highlight
ABSTRACT:
SUBMITTER: Sabol HM
PROVIDER: S-EPMC8589324 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Sabol Hayley M HM Delgado-Calle Jesus J
Journal of cancer metastasis and treatment 20210414
Multiple myeloma (MM) is a hematologic cancer characterized by uncontrolled growth of malignant plasma cells in the bone marrow and currently is incurable. The bone marrow microenvironment plays a critical role in MM. MM cells reside in specialized niches where they interact with multiple marrow cell types, transforming the bone/bone marrow compartment into an ideal microenvironment for the migration, proliferation, and survival of MM cells. In addition, MM cells interact with bone cells to stim ...[more]