RADSex: A computational workflow to study sex determination using restriction site-associated DNA sequencing data.

ABSTRACT: The study of sex determination and sex chromosome organization in nonmodel species has long been technically challenging, but new sequencing methodologies now enable precise and high-throughput identification of sex-specific genomic sequences. In particular, restriction site-associated DNA sequencing (RAD-Seq) is being extensively applied to explore sex determination systems in many plant and animal species. However, software specifically designed to search for and visualize sex-biased markers using RAD-Seq data is lacking. Here, we present RADSex, a computational analysis workflow designed to study the genetic basis of sex determination using RAD-Seq data. RADSex is simple to use, requires few computational resources, makes no prior assumptions about the type of sex-determination system o

SUBMITTER: Feron R 

PROVIDER: S-EPMC8589568 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature