Risk of Infection Associated With Administration of Intravenous Iron: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Intravenous iron is recommended by many clinical guidelines based largely on its effectiveness in reducing anemia. However, the association with important safety outcomes, such as infection, remains uncertain.

Objective

To examine the risk of infection associated with intravenous iron compared with oral iron or no iron.

Data sources

Medline, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched for randomized clinical trials (RCTs) from 1966 to January 31, 2021. Ongoing trials were sought from ClinicalTrials.gov, CENTRAL, and the World Health Organization International Clinical Trials Search Registry Platform.

Study selection

Pairs of reviewers identified RCTs that compared intravenous iron with oral iron or no iron acros

SUBMITTER: Shah AA 

PROVIDER: S-EPMC8590171 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature