Association of Birth Weight With Foveolar Thickness in Adulthood: Results From a Population-Based Study.

ABSTRACT:

Purpose

Low birth weight (BW) is associated with alterations of foveal shape development in childhood-leading to an increased retinal thickness of the fovea. The aim of the present study was to assess whether BW has a long-term effect on foveal retinal thickness (RT) and is still present in adulthood.

Methods

In the German population-based Gutenberg Health Study (GHS), participants were examined with spectral-domain optical coherence tomography. The association between self-reported BW and RT in the foveolar and perifoveal locations was assessed. Multivariable linear regression analyses with adjustment for potential confounders and grading of foveal hypoplasia were performed.

Results

Overall, RT measurements and self-reported BW were available for 2,539 participants (

SUBMITTER: Fieß A 

PROVIDER: S-EPMC8590182 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature