Manifestation of Hippocampal Interictal Discharges on Clinical Scalp EEG Recordings.

ABSTRACT:

Purpose

Epileptiform activity limited to deep sources such as the hippocampus currently lacks reliable scalp correlates. Recent studies, however, have found that a subset of hippocampal interictal discharges may be associated with visible scalp signals, suggesting that some types of hippocampal activity may be monitored noninvasively. The purpose of this study is to characterize the relationship between these scalp waveforms and the underlying intracranial activity.

Methods

Paired intracranial and scalp EEG recordings obtained from 16 patients were used to identify hippocampal interictal discharges. Discharges were grouped by waveform shape, and spike-triggered averages of the intracranial and scalp signals were calculated for each group. Cross-correlation of intracranial an

SUBMITTER: Lee S 

PROVIDER: S-EPMC8590709 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature