Triglyceride glucose-body mass index in identifying high-risk groups of pre-diabetes.

ABSTRACT:

Background

Triglyceride glucose-body mass index (TyG-BMI) has been recommended as an alternative indicator of insulin resistance. However, the association between TyG-BMI and pre-diabetes remains to be elucidated.

Methods

More than 100,000 subjects with normal glucose at baseline received follow-up. The main outcome event of concern was pre-diabetes defined according to the diagnostic criteria recommended by the American Diabetes Association (ADA) in 2018 and the World Health Organization (WHO) in 1999. A Cox proportional hazard regression model was used to evaluate the role of TyG-BMI in identifying people at high risk of pre-diabetes.

Results

At a mean observation period of 3.1 years, the incidence of pre-diabetes in the cohort was 3.70 and 12.31% according to the W

SUBMITTER: Jiang C 

PROVIDER: S-EPMC8590771 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature