Cancer mortality update with an exposure response analysis among styrene-exposed workers in the reinforced plastics boatbuilding industry.

ABSTRACT:

Background

There is sparse and inconsistent evidence of an association between styrene exposure and cancer.

Methods

This study examines mortality patterns in a previously studied cohort of 5201 workers employed in two Washington boat-building facilities, extending follow-up 5 years. Standardized mortality ratios (SMR) were calculated using state rates as referent. Cox regression calculated rate ratios (RR) per year employed in styrene-exposed exposed jobs.

Results

No excess deaths from lymphohematopoietic cancers (LHCs) were observed (SMR: 0.99, 95%CI: 0.74-1.30) when compared to the referent population; however, the relative risk increased with duration of employment in internal analyses. Conversely, lung cancer mortality was significantly elevated (SMR: 1.24, 95%CI:

SUBMITTER: Bertke SJ 

PROVIDER: S-EPMC8590871 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature