A cluster analysis of patients with axial spondyloarthritis using tumour necrosis factor alpha inhibitors based on clinical characteristics.

ABSTRACT:

Background

This study aimed to classify the distinct group of patients with axial spondyloarthritis (SpA) on tumour necrosis factor alpha inhibitors (TNFi) according to the baseline characteristics using a clustering algorithm.

Methods

The clinical characteristics and demographic data of patients with axial SpA included in the Korean College of Rheumatology Biologics and Targeted Therapy registry were investigated. The patterns of disease manifestations were examined using divisive hierarchical cluster analysis. After clustering, we compared the clinical characteristics of patients and the drug survival of TNFi between the classified groups.

Results

A total of 1042 patients were analysed. The cluster analysis classified patients into two groups: axial group predominan

SUBMITTER: Lee S 

PROVIDER: S-EPMC8591959 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature