Clinical Features of Acute Chikungunya Virus Infection in Children and Adults during an Outbreak in the Maldives.

ABSTRACT: The chikungunya virus is an arthritogenic arbovirus that has re-emerged in many tropical and subtropical regions, causing explosive outbreaks. This re-emergence is due to a genomic polymorphism that has increased the vector susceptibility of the virus. The majority of those infected with chikungunya virus exhibit symptoms of fever, rash, and debilitating polyarthralgia or arthritis. Symptoms can persist for weeks, and patients can relapse months later. Fatalities are rare, but individuals of extreme age can develop severe infection. Here, we describe the 2019 outbreak, the second-largest since the virus re-emerged in the Maldives after the 2004 Indian Ocean epidemic, in which a total of 1,470 cases were reported to the Health Ministry. Sixty-seven patients presenting at the main referral t

SUBMITTER: Imad HA 

PROVIDER: S-EPMC8592165 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature