Association of SNPs within TMPRSS6 and BMP2 genes with iron deficiency status in Saudi Arabia.

ABSTRACT:

Background

Globally, iron-deficiency anemia (IDA) remains a major health obstacle. This health condition has been identified in 47% of pre-school students (aged 0 to 5 years), 42% of pregnant females, and 30% of non-pregnant females (aged 15 to 50 years) worldwide according to the WHO. Environmental and genetic factors play a crucial role in the development of IDA; genetic testing has revealed the association of a number of polymorphisms with iron status and serum ferritin.

Aim

The current study aims to reveal the association of TMPRSS6 rs141312 and BMP2 rs235756 with the iron status of females in Saudi Arabia.

Methods

A cohort of 108 female university students aged 18-25 years was randomly selected to participate: 50 healthy and 58 classified as iron deficient. A 3-5

SUBMITTER: Al-Amer OM 

PROVIDER: S-EPMC8592490 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature