Magnetic Resonance Myocardial Feature Tracking in Transfusion-Dependent Myelodysplastic Syndrome.

ABSTRACT:

Background

Myocardial deformation with echocardiography allows early detection of systolic dysfunction and is related to myocardial iron overload (MIO) determined by T2* in hereditary anemias under transfusion support. Our aim was to analyze the diagnostic and prognostic usefulness of magnetic resonance feature tracking (MR-FT) myocardial strain in low-risk myelodysplastic syndromes (LR-MDS) patients.

Methods

Prospective study in transfusion-dependent LR-MDS patients and healthy controls who underwent a cardiac MR-FT. We analyzed the relationships between strain MR-FT and iron overload parameters and its prognostic impact in cardiovascular events and/or death.

Results

Thirty-one patients and thirteen controls were included. MIO (T2* < 20 ms) was detected in 9.7% of pa

SUBMITTER: Alonso-Fernandez-Gatta M 

PROVIDER: S-EPMC8592675 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature