Modelling response strategies for controlling gonorrhoea outbreaks in men who have sex with men in Australia.

ABSTRACT: The ability to treat gonorrhoea with current first-line drugs is threatened by the global spread of extensively drug resistant (XDR) Neisseria gonorrhoeae (NG) strains. In Australia, urban transmission is high among men who have sex with men (MSM) and importation of an XDR NG strain in this population could result in an epidemic that would be difficult and costly to control. An individual-based, anatomical site-specific mathematical model of NG transmission among Australian MSM was developed and used to evaluate the potential for elimination of an imported NG strain under a range of case-based and population-based test-and-treat strategies. When initiated upon detection of the imported strain, these strategies enhance the probability of elimination and reduce the outbreak size compared wit

SUBMITTER: Duan Q 

PROVIDER: S-EPMC8594806 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature